Anti-KCNU1/Slo3 pH-Sensitive Maxi-K+ Channel Antibody 75-056 from Antibodies Inc.

Product Specs
ItemAnti-KCNU1/Slo3 pH-Sensitive Maxi-K+ Channel Antibody
CompanyAntibodies Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog Number75-056
Antibody TypePrimary Antibody
ClonalityMonoclonal
ReactivityMouse, Xenopus
Regulatory StatusThese antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans
FormatLiquid, Purified by Protein A chromatography
ApplicationsEM, ICC, IP, WB
CloneN2/16
Gene NameKcnu1 Kcnma3 Ksper Slo3
HostMouse
Quantity100 µL
Molecular Weight115 kDa
TargetKCNU1/Slo3 pH-sensitive maxi-K+ channel
IsotypeIgG1
Conjugate/TagUnconjugated
Brand/TrademarkNeuroMab
ImmunogenFusion protein amino acids 1052-1121 of mouse Slo3 (accession number O54982) produced recombinantly in E. Coli
ValidationEach new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern
NCBI Gene AliasesKcnm, Kcnma3, S, Slo3, mSlo3

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(1) A cytoplasmic Slo3 isoform is expressed in somatic tissuesMolecular biology reportsOctober 1, 2019Chávez JC, Vicens A, Wrighton DC, Andrade-López K, Beltrán C, Gutiérrez RM, Lippiat JD, Treviño CL.

(2) SLO3 auxiliary subunit LRRC52 controls gating of sperm KSPER currents and is critical for normal fertilityProceedings of the National Academy of Sciences of the United States of AmericaFebruary 24, 2015Zeng XH, Yang C, Xia XM, Liu M, Lingle CJ.

(3) LRRC52 (leucine-rich-repeat-containing protein 52), a testis-specific auxiliary subunit of the alkalization-activated Slo3 channelProceedings of the National Academy of Sciences of the United States of AmericaNovember 29, 2011Yang C, Zeng XH, Zhou Y, Xia XM, Lingle CJ.

(4) Deletion of the Slo3 gene abolishes alkalization-activated K+ current in mouse spermatozoaProceedings of the National Academy of Sciences of the United States of AmericaApril 5, 2011Zeng XH, Yang C, Kim ST, Lingle CJ, Xia XM.

(5) The SLO3 sperm-specific potassium channel plays a vital role in male fertilityFEBS lettersMarch 5, 2010Santi CM, Martínez-López P, de la Vega-Beltrán JL, Butler A, Alisio A, Darszon A, Salkoff L.

(8) Mouse sperm K+ currents stimulated by pH and cAMP possibly coded by Slo3 channelsBiochemical and biophysical research communicationsApril 3, 2009Martínez-López P, Santi CM, Treviño CL, Ocampo-Gutiérrez AY, Acevedo JJ, Alisio A, Salkoff LB, Darszon A.

Anti-KCNU1/Slo3 pH-Sensitive Maxi-K+ Channel Antibody from Antibodies Inc.